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ID:993 Gentamicin
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Description Gentamicin is an aminoglycoside antibiotic, used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms. However, gentamicin is not used for Neisseria gonorrhoeae, Neisseria meningitidis or Legionella pneumophila. Gentamicin is also ototoxic and nephrotoxic, with this toxicity remaining a major problem in clinical use.
Indication Antibiotic monitoring
Additional Info As of 17.6.11 processed by the department of Blood Sciences (biochemistry) - not Microbiology. Advice on interpretation can be found via the microbiology section of the Pathology website: http://www.pathology.leedsth.nhs.uk/pathology/Departments/Microbiology/MicroAntibioticMonitoringGuidelines.aspx If you are not able to interpret the Gentamicin level result safely please contact the microbiology department for clinical advice. Please note: test can only be added to samples within 8 hours of collection
Concurrent Testsna
Dietary Requirementsna
Interpretation

DepartmentBlood Sciences
SampleBlood
TubeSerum Gel
Tube Picture
Collection Conditions Serum (with or without gel) and plasma (EDTA/lithium heparin) samples acceptable. Pre, post and 6-14 hrs post dose for once daily gent.If the patient is not on a once daily regimen, samples should be taken 1 hour post dose
Min. Vol 1mL
Freq.

Ref. Range (Male) s. Ref Range Comment
Ref. Range (Female) s. Ref Range Comment
Ref. Range (Paed) s. Ref Range Comment
Ref. Range Notes Adult Ref. Range: Multi dose Pre dose <2mg/L Post dose 5-10 mg/L (1 hour) Once daily see Ref notes link below Paediatric Ref. Range: Multi dose Pre dose <2mg/L Post dose 5-10 mg/L (1hour) Once daily see Ref notes link below Multi dose therapy: See Antimicrobial monitoring http://www.pathology.leedsth.nhs.uk/pathology/Departments/Microbiology/MicroAntibioticMonitoringGuidelines.aspx Once Daily therapy: See Leeds Health Pathways Leeds Health Pathways is only available via NHSnet at http://nww.lhp.leedsth.nhs.uk
Unitsmg/L
IP Acute TATRefer to Website
IP Routine TATRefer to Website
GP Acute TATRefer to Website
GP Routine TATRefer to Website
Turnround CommentNA

Originally edited by : na. Review due on 31/05/2018 09:34:23. Published By on 31/05/2017 09:34:23.