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ID:98 Haptoglobin
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DescriptionHaptoglobin is a serum glycoprotein which binds free haemoglobin. The haptoglobin-Hb complex is cleared by the reticuloendothelial system.
IndicationIntravascular haemolysis.
Additional InfoHaptoglobin is an "acute-phase" protein; this means that it will be increased in many inflammatory diseases such as ulcerative colitis, acute rheumatic disease, heart attack and severe infection. This can complicate the interpretation of the haptoglobin results. Haptoglobin testing is not used to help diagnose or monitor these conditions. Haptoglobin levels may be affected by massive blood loss and by conditions associated with kidney dysfunction, as well as liver disease. Drugs that can increase haptoglobin levels include androgens and corticosteroids such as prednisolone. Drugs that can decrease haptoglobin concentrations include isoniazid, quinidine, streptomycin and birth control pills. [Source of information: https://labtestsonline.org.uk/tests/haptoglobin]
Concurrent Testsna
Dietary Requirementsna
InterpretationHaptoglobin is depleted from serum in states of intravascular haemolysis. Haptoglobin rises as part of the acute phase response.

DepartmentClinical Immunology
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol2 mL
Freq.Weekdays

Ref. Range (Male)0.5 - 2.0
Ref. Range (Female)0.4 - 1.6
Ref. Range (Paed)
Ref. Range Notes
Unitsg/L
IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT7 days
Turnround CommentNA

Originally edited by : JHB. Review due on 01/06/2019 09:56:26. Published By BD on 01/06/2018 09:56:26.