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ID:927 Array CGH
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DescriptionArray CGH is a technique for detecting abnormalities of genomic copy number.
IndicationPatients presenting with unexplained learning difficulties / developmental delay / behavioural problems (including autism and referrals for the fragile X phenotype). Patients with dysmorphism / multiple congenital abnormalities suggestive of a chromosome abnormality.
Additional InfoIt is a high resolution whole genome screen which detects genetic imbalances at a greater resolution (60Kb) compared with karyotyping (5-10Mb), ie a ~1000 fold increase in resolution. This increase in resolution detects a higher number of genomic gains and losses (imbalances) directly related to the patientís phenotype than can be seen using karyotype + MLPA. Array CGH also accurately identifies the type and location of the pathogenic genes involved in chromosome imbalances.
Concurrent Testsna
Dietary Requirementsna
Interpretation

DepartmentGenetics - Cytogenetics
SampleBlood
TubeEDTA (Haem)
Tube Picture
Collection ConditionsThe cytogenetics laboratory will require a minimum of 1ml peripheral blood in an EDTA tube (purple top) and a minimum of 1ml peripheral blood in a Lithium Heparin tube (green or orange top) with an array CGH referral card completed with comprehensive clinical details.
Min. Vol
Freq.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT- Not Defined -
IP Routine TAT- Not Defined -
GP Acute TAT- Not Defined -
GP Routine TAT- Not Defined -
Turnround CommentNA

Originally edited by : na. Review due on 17/01/2014 15:41:45. Published By Josie Hayes on 17/01/2013 15:41:45.