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ID:920 TmP/GFR
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Description Renal Tubular maximum reabsorption rate of phosphate to glomerular filtration rate. Tests involved in this investigation are serum and urine phosphate and creatinine
Indication 1) Conditions that cause phosphate redistribution (e.g. glucose infusion, respiratory alkalosis) can increase phosphate loss, so if hypophosphataemia persists, a low (fasting) TmP/GFR indicates the need for phosphate replacement. In the treatment of severe phosphate deficiency, TmP/GFR can be used as an indicator of intracellular repletion. 2) The measurement of TmP/GFR (together with plasma 1,25 OH Vit D is required for the diagnosis of X linked hypophosphataemic rickets with hypercalciuria. 3) Fanconi's syndrome
Additional Info Fasting serum (gold top tube) required for serum phosphate and creatinine, spot urine sample (plain universal) required for urine phosphate and creatinine. PLEASE CONTACT DUTY BIOCHEMIST IF THIS INVESTIGATION IS REQUIRED. AVAILABLE ON REQUEST
Concurrent Testsna
Dietary Requirementsna
InterpretationReduced in primary hyperparathyroidism, renal tubular disorders, osteomalacia, fanconi's syndrome. Increased in children, acromegaly and hypothyroidism

Department* Not Specified *
TubeSerum Gel
Tube Picture
Collection ConditionsPatient should be fasted (overnight if possible). The first voided urine is discarded. The next (untimed) urine is collected and a blood specimen taken
Min. Vol 2 - 5 mL (urine)

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes 0.80 to 1.35 mmol/L
Units - Not Defined -
IP Acute TAT- Not Defined -
IP Routine TAT- Not Defined -
GP Acute TAT- Not Defined -
GP Routine TAT- Not Defined -
Turnround CommentNA

Originally edited by : na. Review due on 10/11/2015 16:22:13. Published By dan carless on 10/11/2014 16:22:13.