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ID:895 Kasper Inhibitor Screen
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DescriptionA sensitive inhibitor screen designed to detect the presence of FVIII & FIX inhibitors in the treatment of haemophilia patients
IndicationAll treated haemophilia A & B patients should undergo inhibitor screening.
Additional InfoThis method can be adapted to screen for other coagulation factors. If this screen is positive, then a Bethesda inhibitor assay should be run.
Concurrent TestsFVIII or FIX assays
Dietary RequirementsNone
InterpretationNo inhibitor detected if the difference between the patients and control plasmas is less than 12 seconds. A result between 12 and 20 seconds may be equivocal depending upon clinical history. Reported as positive or negative.

DepartmentSpecialist Laboratory Medicine
SampleBlood
TubeCoagulation
Tube Picture
Collection ConditionsCorrectly filled citrate tubes x 2
Min. Vol
Freq.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes Critical telephone values: All new / relapsed positive screens will be phoned to the appropriate haematology consultant
UnitsPositive/Negative
IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT- Contact Laboratory
Turnround CommentSpecialist test only requested as part of an investigation by a haematologist.

Originally edited by : RJAR. Review due on 18/06/2019 10:36:03. Published By RJAR on 18/06/2018 10:36:03.