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ID:88 Gastric Parietal Cell Antibodies
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DescriptionGastric parietal cell (GPC) antibodies are directed against the gastric H/K ATPase.
IndicationPernicious anaemia. Atrophic gastritis. Autoimmune gastritis.
Additional InfoAnti-GPC antibodies are assayed as part of a panel of tests including liver autoantibodies.
Concurrent Testsna
Dietary Requirementsna
InterpretationParietal cell antibodies are found in about 90% of Caucasian patients with pernicious anaemia. Parietal cell antibodies are not disease specific, they can be detected in patients with chronic atropic gastritis, gastric ulcers, Sjogren's syndrome, other autoimmune endroctinopathis and in up to 7% of healthy individuals. Where GPC Ab are detected in asymptomatic patients, 3% per year may go on th develop pernicious anaemia.

DepartmentClinical Immunology
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions.
Min. Vol5 mL

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesQualitative - Pos/Neg
Units - Not Defined -
IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT7 days
Turnround CommentNA

Originally edited by : JHB. Review due on 14/09/2018 14:28:00. Published By AM on 14/09/2017 14:28:00.