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ID:859 Bordetella Pertussis serology
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DescriptionPertussis (or whooping cough) is an infection of the respiratory system and characterized by a “whooping” sound when the person breathes in. In the US it killed 5,000 to 10,000 people per year before a vaccine was available. A nasopharyngeal or an oropharynx swab is sent to the bacteriology laboratory for Gram stain (Gram negative, coccobacilli, diplococci arrangement), growth on Bordet-Gengou agar or BCYE plate with added cephalosporin to select for the organism, which shows mercury-drop-like colonies. The organism is oxidase positive, but urease, nitrase, and citrate negative. It is also non-motile.
Indication Serology test only performed as a clinical diagnosis, not to check for vaccination status
Additional InfoBordetella pertussis infects its host by colonizing lung epithelial cells. The bacterium contains a surface protein, filamentous hemagglutinin, which binds to sulfatides that are found on cilia of epithelial cells. Once anchored, the bacterium produces tracheal cytotoxin, which stops the cilia from beating. This prevents the cilia from clearing debris from the lungs, so the body responds by sending the host into a coughing fit. These coughs expel some bacteria into the air, which are free to infect other hosts. PCR is aslo available.(referred test)
Concurrent Testsna
Dietary Requirementsna
Interpretation Results in IU/ml IgG. In the Asence of recent vaccination, >70 IU/ml = consistent with recent infection.

DepartmentMicrobiology
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol4ml
Freq.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT28 days
IP Routine TAT28 days
GP Acute TAT28 days
GP Routine TAT28 days
Turnround CommentNA

Originally edited by : D Bennett. Review due on 27/02/2019 14:59:40. Published By K Roberts on 27/02/2018 14:59:40.