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ID:840 Anti-C1q antibodies
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Description Autoantibodies to the complement classical pathway component C1q.
IndicationAnti-C1q antibodies are associated with Hypocomplementaemic Urticarial Vasculitis (HUV) and have been reported in SLE, especially those with renal involvement (Lupus Nephritis). Anti-C1q antibodies are associated with a low complement C4 and often a low complement C3 as well.
Additional Info
Concurrent Testsna
Dietary Requirementsna
Interpretation Anti-C1q Ab are used in the diagnosis of HUV. Anti-C1q Ab can also be found in patients with SLE, particularly those with renal involvement. Patients with Low titres of anti-C1q Ab are at low risk of developing an active lupus nephritis; thoses with a high anti-C1q Ab titre have a high risk of developing an active lupus nephritis.

DepartmentClinical Immunology
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol
Freq.

Ref. Range (Male)0-15
Ref. Range (Female) 0-15
Ref. Range (Paed)
Ref. Range Notes <15U/mL in normal reference range.
Unitsu/mL
IP Acute TAT- Not Defined -
IP Routine TAT10 days
GP Acute TAT- Not Defined -
GP Routine TAT10 days
Turnround CommentTurn around time provided by the referral laboratory. Please allow additional time for sample dispatch and return of results.

Originally edited by : BD. Review due on 14/09/2018 14:16:53. Published By AM on 14/09/2017 14:16:53.