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ID:78 Dihydrotestosterone
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Description5-alpha-reductase converts testosterone, DHEA and androstenedione into DHT. DHT is responsible for external mascularisation of males. Hence its deficiency leads to ambiguous genitalia in males. Circulating concentrations are of little significance in females.
IndicationTo investigate ambiguous genitalia in neonates and young children. To investigate suspicion of 5alpha- reductase deficiency
Additional InfoSend to: Specialist Laboratory Medicine Block 46 St James hospital Beckett Street Leeds LS9 7TF
Concurrent Testsna
Dietary Requirementsna
InterpretationVery low levels could indicate an enzyme deficiency

DepartmentSpecialist Laboratory Medicine
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol2.5mL
Freq.Monthly

Ref. Range (Male)0.9 - 2.9
Ref. Range (Female)0.2 - 1.0
Ref. Range (Paed)
Ref. Range Notes
Unitsnmol/L
IP Acute TAT- Contact Laboratory
IP Routine TAT35 days
GP Acute TAT- Contact Laboratory
GP Routine TAT35 days
Turnround CommentNA

Originally edited by : JHB. Review due on 23/01/2020 09:07:48. Published By RB on 23/01/2019 09:07:48.