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ID:698 Clobazam
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DescriptionAnti-convulsant drug
IndicationTherapeutic drug monitoring (TDM)
Additional Info
Concurrent Testsna
Dietary Requirementsna
InterpretationNo correlation between either seizure control or toxicity has yet been established, but the majority of patients receiving treatment with conventional doses of clobazam have plasma concentrations below 200 g/L for the parent drug and 2000 g/L for the desmethyl metabolite. Desmethylclobazam has a longer T1/2 and therefore reaches higher plasma concentration.

DepartmentBiochemistry
SampleBlood
TubeSerum (No Gel)
Tube Picture
Collection ConditionsDo NOT use gel seperator tubes. Heparin tubes (no gel) and EDTA samples are also acceptable
Min. Vol2 mL
Freq.Referred to external laboratory

Ref. Range (Male) 0.1 - 0.4 mg/L
Ref. Range (Female) 0.1 - 0.4 mg/L
Ref. Range (Paed)
Ref. Range Notes0.1-0.4
Unitsmg/L
IP Acute TATRefer to Website
IP Routine TAT7 days
GP Acute TATRefer to Website
GP Routine TATRefer to Website
Turnround CommentRobert Haddon:HutchingsAD@cardiff.ac.uk

Originally edited by : . Review due on 22/11/2018 10:24:06. Published By RB on 22/11/2017 10:24:06.