Trust Homepage > Pathology Homepage

Test and Tubes Database
ID:696 Olanzapine
Search Links: General Info : Protocols : LabTestsOnline

DescriptionOlanzapine (Zyprexa, Lilly) is an atypical antipsychotic agent with structural similarities to clozapine. Extensively metabolised in the liver and excreted by the kidney. It is not thought that any of the metabolites are pharmacologically active. No metabolites accumulate in plasma.
IndicationTherapeutic drug monitoring (TDM)
Additional Info
Concurrent Testsna
Dietary Requirementsna
InterpretationMean plasma olanzapine half-lives are longer in elderly patients (65 y or more) (51.8 h) as compared to adults (33.8 h) and in females (36.7 h) as compared to males (32.3 h). The limit of sensitivity of the assay is 2 g/L (1 mL sample).

DepartmentBiochemistry
SamplePlasma
TubeEDTA
Tube Picture
Collection ConditionsDo NOT use gel seperator tubes
Min. Vol2 mL
Freq.Referred to external laboratory

Ref. Range (Male)20 -40
Ref. Range (Female)20 -40
Ref. Range (Paed)
Ref. Range Notes 20-40
Unitsug/L
IP Acute TAT1 week
IP Routine TAT1 week
GP Acute TAT1 week
GP Routine TAT1 week
Turnround CommentRobert Haddon:HutchingsAD@cardiff.ac.uk

Originally edited by : . Review due on 17/10/2017. Published By on 17/10/2017.