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Test and Tubes Database
ID:694 Topiramate
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DescriptionTopiramate is a relatively new anticonvulsant drug. It is rapidly and efficiently absorbed from the GI tract after which it is eliminated, predominantly unchanged, via the renal route with a plasma t of 20-30 hrs. A proportion of the drug undergoes hepatic metabolism by oxidative pathways and the clearance is increased by enzyme inducing drugs.
IndicationTherapeutic drug monitoring (TDM) when modifying treatment or to establish baseline values. Also to check compliance or if toxicity is suspected.
Additional Info
Concurrent Testsna
Dietary Requirementsna
Interpretation

DepartmentBiochemistry
SamplePlasma
TubeEDTA
Tube Picture
Collection ConditionsDo NOT use gel seprator tubes
Min. Vol2 mL
Freq.Referrred to external laboratory

Ref. Range (Male)5 - 20
Ref. Range (Female)5 - 20
Ref. Range (Paed)
Ref. Range Notes5 to 20
Unitsmg/L
IP Acute TAT1 week
IP Routine TAT1 week
GP Acute TAT1 week
GP Routine TAT1 week
Turnround CommentJoanne Rogers:HutchingsAD@cardiff.ac.uk

Originally edited by : . Review due on 17/10/2017. Published By on 17/10/2017.