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Test and Tubes Database
ID:693 Gabapentin
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DescriptionThis test is no longer routinely available. Please contact the Duty Biochemist for further discussion if required Anticonvulsant drug.
IndicationTherapeutic drug monitoring (TDM) . To assess compliance or suspected toxicity. TDM should be applied when modifying treatment in any way or to establish baseline values during successful treatment.
Additional InfoFollowing absorption gabapentin is cleared entirely unchanged by the kidneys with a plasma elimination half-life of 5-6 hrs and the drug is not protein bound. Adverse drug reactions are mainly CNS related and associated with elevated drug concentrations in plasma/serum. A reasonable correlation has been demonstrated between plasma/serum levels and seizure control.
Concurrent Testsna
Dietary Requirementsna
InterpretationThe drug is absorbed from the proximal small bowel into the blood stream by the L-amino acid transport system with bioavailability of gabapentin reported to be dose-dependent

DepartmentBiochemistry
SampleBlood
TubeSerum (No Gel)
Tube Picture
Collection ConditionsGel separator tubes should NOT be used
Min. Vol1 Ml
Freq.Referred to external laboratory

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes 43862
Unitsmg/L
IP Acute TAT- Contact Laboratory
IP Routine TATAt least 1 week
GP Acute TAT- Contact Laboratory
GP Routine TAT1 week
Turnround CommentDr Alun Hutchings:HutchingsAD@cardiff.ac.uk

Originally edited by : . Review due on 23/11/2018 16:45:29. Published By on 23/11/2017 16:45:29.