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ID:59 Cholinesterase Activity and Phenotype
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DescriptionCholinesterase deficiency will result in prolonged paralysis after the use of muscle relaxants for operative surgery. Please contact Clinical Biochemistry if this assay is required.
IndicationScoline apnoea. Family studies of patients with cholinesterase deficiency. Pesticide workers.
Additional InfoCholinesterase phenotype is used to predict susceptibility to prolonged apnoea after administration of suxamethonium or mivacurium.
Concurrent Testsna
Dietary Requirementsna

Department* Not Specified *
TubeEDTA (Haem)
Tube Picture
Collection ConditionsSamples should not be collected less than 12 hours after the administration of suxamethonium or mivacurium. If patient has been treated with with fresh frozen plasma or a cholinesterase preparation a period of at least 6 weeks should be allowed before a sample is collected.
Min. Vol1 mL

Ref. Range (Male)See notes
Ref. Range (Female)see notes
Ref. Range (Paed)
Ref. Range NotesCholinesterase activity ref range: <5300 U/L
IP Acute TATAbout 2 weeks
IP Routine TATAbout 2 weeks
GP Acute TATAbout 2 weeks
GP Routine TATAbout 2 weeks
Turnround CommentActivity: 1-2 weeks (contact referral lab if surgery is imminent). Phenotype: 2-4 weeks. Genotype: 10-12 weeks. Dr Roberta

Originally edited by : JHB. Review due on 22/11/2018 10:16:43. Published By RB on 22/11/2017 10:16:43.