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ID:536 Aspergillus antigen
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DescriptionThis test detects the presence of the Aspergillus antigen galactomannan in serum or bronchoalveolar lavage using a commercial manual ELISA kit.
IndicationAppropriate for the diagnosis of invasive aspergillosis in patients who are currently or have recently been neutropenic. This test may have value in other immunocompromised patients but is not usually indicated in patients who are likely to have reasonable immune responses where the Aspergillus antibody test is more appropriate.
Additional Info
Concurrent Tests
Dietary Requirements
InterpretationLevels of galactomannan above the cutoff of an index of 0.5 are significant. Negative results are typically around 0.1 or less and results between 0.3 and 0.5 may increase the index of suspicion and indicate repeat testing. Any positives should be confirmed by repeat testing.

SampleBlood, Serum, CSF or BAL
TubeSerum Gel Tube
Tube Picture
Collection ConditionsCSF or BAL samples should be collected in a sterile screw top container.
Min. Vol5ml blood 700ul serum, CSF or BAL

Ref. Range (Male)0-0.49
Ref. Range (Female)0-0.49
Ref. Range (Paed)0-0.49
Ref. Range NotesNote positives are always confirmed on the same specimen and a repeat specimen is recommended. Note we report indexes of >0.49 as positive on BALs, but generally only indexes of >0.99 are significant for BAL samples.
Units - Not Defined -
IP Acute TAT3 days
IP Routine TAT3 days
GP Acute TAT3 days
GP Routine TAT3 days
Turnround Comment95% Turnaround times This test is usually performed 3 times a week. Results may be available considerably earlier than stated turnaround time.

Originally edited by : Richard Barton. Review due on 29/04/2020 13:50:03. Published By Kasia Okurowska on 29/04/2019 13:50:03.