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ID:527 Acanthamoeba investigation for chronic granulomatous meningitis
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DescriptionAcanthomoeba belong to the group of free-living amoeba and can cause a chronic granulomatous meningitis (CGM) which carries a high mortality. Samples are referred from Microbiology for Molecular Detection by PCR to Micropathology Ltd. Turnaround time is 7 days. This test is not yet validated for this sample type.
IndicationThere are no characteristic clinical or diagnostic findings that would suggest CGM. Consider in patients with symptoms of meningitis/encephalitis where cerebrospinal fluid (CSF) examination is negative for routine organisms or patient does not respond to conventional antibiotic therapy. White blood cells must be present for referral.
Additional Info Ensure sample is labelled and additional CSF sample is sent if routine culture and cell count is required. High risk stickers should be added to form and sample.
Concurrent Testsna
Dietary Requirementsna
Interpretation A positive result will be issued as Acanthamoeba DNA detected. A negative result will be issued as Acanthamoeba DNA not detected

DepartmentMicrobiology
SampleCSF
TubePlain Universal
Tube Picture
Collection ConditionsDo not freeze down sample. Keep refrigerated only.
Min. Vol 0.5ml
Freq.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT14 days
IP Routine TAT14 days
GP Acute TAT14 days
GP Routine TAT14 days
Turnround CommentNegative results may be available considerably earlier than stated turnaround time.

Originally edited by : D Bennett. Review due on 10/05/2018 15:06:18. Published By K Roberts on 10/05/2017 15:06:18.