|Description||Acanthomoeba belong to the group of free-living amoeba and can cause a chronic granulomatous meningitis (CGM) which carries a high mortality. Samples are referred from Microbiology for Molecular Detection by PCR to Micropathology Ltd. Turnaround time is 7 days. This test is not yet validated for this sample type.|
|Indication||There are no characteristic clinical or diagnostic findings that would suggest CGM. Consider in patients with symptoms of meningitis/encephalitis where cerebrospinal fluid (CSF) examination is negative for routine organisms or patient does not respond to conventional antibiotic therapy.
White blood cells must be present for referral.|
|Additional Info|| Ensure sample is labelled and additional CSF sample is sent if routine culture and cell count is required.
High risk stickers should be added to form and sample.|
|Interpretation|| A positive result will be issued as Acanthamoeba DNA detected. A negative result will be issued as Acanthamoeba DNA not detected|
|Collection Conditions||Do not freeze down sample. Keep refrigerated only.
|Min. Vol|| 0.5ml|
|Ref. Range (Male)|| |
|Ref. Range (Female)|| |
|Ref. Range (Paed)|| |
|Ref. Range Notes||
|Units|| - Not Defined -|
|IP Acute TAT||14 days|
|IP Routine TAT||14 days|
|GP Acute TAT||14 days|
|GP Routine TAT||14 days|
|Turnround Comment||Negative results may be available considerably earlier than stated turnaround time.|
Originally edited by : D Bennett. Review due on 10/05/2018 15:06:18. Published By K Roberts on 10/05/2017 15:06:18.