|Description||For drug monitoring purposes, blood should not be drawn until a steady state has been attained. This will not be achieved until 2-4 weeks after starting therapy. Following the establishment of a steady state, further samples casn be taken after 3-4 days.|
|Indication||Therapeutic Drug Monitoring (anti convulsant).
|Additional Info||The concentration of carbamazepine may be increased in liver disease as it is completely metabolised by the liver. Carbamazepine may also induce the hepatic metabolism of other drugs by enzyme induction. PLEASE NOTE: TEST CAN ONLY BE ADDED TO A SAMPLE WITHIN 8 HOURS OF COLLECTION|
|Interpretation||Serum/plasma levels only moderately correlate to dose.|
|Tube||Serum or Heparin|
|Collection Conditions||Use Gold top (serum gel) tube except for Intensive care units, renal unit, transplant unit, patients on IV heparin (use Green/yellow top tube for these patients).|
|Min. Vol||1 mL|
|Ref. Range (Male)||4 - 12 mg/L (Note Units)|
|Ref. Range (Female)|| |
|Ref. Range (Paed)|| |
|Ref. Range Notes||NOTE: Reporting units changed from mmol/L to mg/L May 1, 2007.
|IP Acute TAT||Refer to Website|
|IP Routine TAT||Refer to Website|
|GP Acute TAT||- Contact Laboratory|
|GP Routine TAT||Refer to Website|
Originally edited by : MC. Review due on 24/05/2017 08:04:58. Published By Sylvia Mclellan on 24/05/2016 08:04:58.