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ID:460 Chromogranin A
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DescriptionTest is not routinely available. Request should be discussed with the on duty biochemist (ext 26922).
IndicationFollow up and management of patients with neuroendocrine tumours.
Additional InfoChromagranin A is useful in the monitoring of gastroenteropancreatic tumours, and follow up of patients with liver metastases. Also a useful marker in lung carcinoids and neuroblastomas. Chromagranin A is the major protein within the catecholamine storage vesicles of adrenal medulla. When catecholamines are released, chromagranin is released. It is also released with polypeptide hormones from other endocrine tissues: pancreatic islet cells, enteroendocrine cells, parathyroid chief cells, thyroid parafollicular C cells, and anterior pituitary cells.
Concurrent Testsna
Dietary RequirementsMust be FASTING > 10 hr.
InterpretationChromagranin may be elevated in patients with various endocrine neoplasms.

DepartmentBiochemistry
SampleSerum or Heparin
TubeSerum or Heparin
Tube Picture
Collection ConditionsSample should be sent to laboratory IMMEDIATELY. Sample will be stored for a month.
Min. Vol2 ml
Freq.Referred to external laboratory

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes <6 nmol/L
Units - Not Defined -
IP Acute TATAbout 2 weeks
IP Routine TATAbout 2 weeks
GP Acute TATAbout 2 weeks
GP Routine TATAbout 2 weeks
Turnround CommentKevin Green:kevin.green@sth.nhs.uk / Laura.Price@sth.nhs.uk

Originally edited by : . Review due on 22/11/2018 10:19:22. Published By dan carless on 22/11/2017 10:19:22.