|Description||Test is not routinely available. Request should be discussed with the on duty biochemist (ext 26922).|
|Indication||Follow up and management of patients with neuroendocrine tumours.
|Additional Info||Chromagranin A is useful in the monitoring of gastroenteropancreatic tumours, and follow up of patients with liver metastases. Also a useful marker in lung carcinoids and neuroblastomas. Chromagranin A is the major protein within the catecholamine storage vesicles of adrenal medulla. When catecholamines are released, chromagranin is released. It is also released with polypeptide hormones from other endocrine tissues: pancreatic islet cells, enteroendocrine cells, parathyroid chief cells, thyroid parafollicular C cells, and anterior pituitary cells.
|Dietary Requirements||Must be FASTING > 10 hr.|
|Interpretation||Chromagranin may be elevated in patients with various endocrine neoplasms.
|Sample||Serum or Heparin|
|Tube||Serum or Heparin|
|Collection Conditions||Sample should be sent to laboratory IMMEDIATELY. Sample will be stored for a month.|
|Min. Vol||2 ml|
|Freq.||Referred to external laboratory|
|Ref. Range (Male)|| |
|Ref. Range (Female)|| |
|Ref. Range (Paed)|| |
|Ref. Range Notes|| <6 nmol/L|
|Units|| - Not Defined -|
|IP Acute TAT||About 2 weeks|
|IP Routine TAT||About 2 weeks|
|GP Acute TAT||About 2 weeks|
|GP Routine TAT||About 2 weeks|
|Turnround Comment||Kevin Green:firstname.lastname@example.org / Laura.Price@sth.nhs.uk|
Originally edited by : . Review due on 22/11/2018 10:19:22. Published By dan carless on 22/11/2017 10:19:22.