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ID:341 Free Fatty Acids
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DescriptionUsed in the investigation of ketolytic defects, and may be useful in the diagnosis of hyperinsulinism or fat oxidation defects.
Indication? Hyperinsulinism, ? Fat oxidation defects (e.g. MCADD), ? Ketolytic defects (e.g. beta ketothiolase deficiency), ketoacidotic states (e.g. alcoholic).
Additional InfoFor hyperinsulism and fat oxidation defects the plasma glucose should be less than 2.5mmol/L for analysis to be valid. For ketolytic defect investigation the test should be performed whatever the glucose. Sometimes used in investigation of various ketoacidotic states.
Concurrent TestsHydroxybutyrate
Dietary Requirementsna
InterpretationFor hyperinsulism, fat oxidation defects and ketolytic defects refer to Paediatric Biochemist at SJUH (ext 64256).

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Collection ConditionsMUST BE FLUORIDE OXALATE BLOOD. Fluoride heparin is NOT acceptable (heparin activates lipoprotein lipase and causes fatty acids to increase).
Min. Vol0.5 mL
Freq.Referred to external laboratory

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesInterpreted in relation to the 3-hydroxybutyrate conentration.
IP Acute TAT- Contact Laboratory
IP Routine TAT5 days
GP Acute TAT- Contact Laboratory
GP Routine TAT- Contact Laboratory
Turnround CommentNA

Originally edited by : . Review due on 22/11/2018 12:07:12. Published By RB on 22/11/2017 12:07:12.