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ID:317 Renin Activity (PRA)
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DescriptionRenin is secreted from the kidney and converts angiotensinogen to angiotensin. The latter stimulates aldosterone production.
IndicationUnexplained Hypertension
Additional Info Send to: Specialist Laboratory Medicine Block 46 St James hospital Beckett Street Leeds LS9 7TF
Concurrent TestsAldosterone
Dietary Requirementsna
InterpretationValues can be very high in neonate (>50nmol/L/h), and low in the elderly

DepartmentSpecialist Laboratory Medicine
SampleBlood
TubeHeparin
Tube Picture
Collection ConditionsRenin is activated when on ice which invalidates the test. Send to the laboratory ASAP but NOT on ice. Please use a red bag to ensure prompt attention. NOTE the tube required for this test is heparin without gel. (Green and black top) EDTA tube also acceptable
Min. Vol1 mL
Freq.Weekly

Ref. Range (Male)See note
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes1.1-2.7 nmol/L/h at 08:00h after overnight recumbency. 2.8-4.5 nmol/L/h at 08:30h after 30 mins ambulant. 0.5-3.5 nmol/L/h random sample. These ranges from adults 20-40yrs with sodium intake 100-150mmol/day and potassium intake 50-100mmol/day
Unitsnmol/L/h
IP Acute TAT- Contact Laboratory
IP Routine TAT21 days
GP Acute TAT- Contact Laboratory
GP Routine TAT21 days
Turnround CommentNA

Originally edited by : . Review due on 23/01/2020 08:53:44. Published By RB on 23/01/2019 08:53:44.