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ID:30 Apolipoprotein-E Genotyping
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DescriptionThis test is no longer routinely available. Please contact the Duty Biochemist for further discussion if required
IndicationGenotyping helpful when phenotyping is difficult to interpret due to post-translational modification of Apo E molecules.
Additional InfoAn Apo-E 2:2 genotype is used to diagnose type III hyperlipidaemia. This is usually suggested by a mixed hyperlipidaemia often with a history of eruptive xanthomata. E4 risk factor in Alzheimer's.
Concurrent Testsna
Dietary Requirementsna
Interpretation95% patients with type III hyperlipidaemia have E2/E2 genotype.

DepartmentBiochemistry
SampleBlood
TubeEDTA (Haem)
Tube Picture
Collection ConditionsNo restrictions.
Min. Vol1 mL
Freq.Referred to external laboratory

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT14 days
IP Routine TAT14 days
GP Acute TAT14 days
GP Routine TAT14 days
Turnround CommentDr Denise Darby:denise.darby@nhs.net / Phillip.Monaghan@christie.nhs.uk

Originally edited by : JHB. Review due on 23/11/2018 16:37:46. Published By on 23/11/2017 16:37:46.