Trust Homepage > Pathology Homepage

Test and Tubes Database
ID:287 Protein C (Part of Thrombophillia screen)
Search Links: General Info : Protocols : LabTestsOnline

DescriptionProtein C is a naturally occuring inhibitor of the coagulation pathway.It is converted to activated protein C (APC) by thrombin in the presence of thrombomodulin. APC inactivates activated factors V and VIII. Protein C deficiency has been shown to be a risk factor for thrombosis.
IndicationInvestigation of possible thrombotic tendencies
Additional InfoProtein C is a vitamin K dependent protein and levels are therefore diminished during warfarin therapy
Concurrent TestsPart of Thrombophilia screen (Antithrombin, Protein S, FV and FII gene mutations)
Dietary RequirementsNone
InterpretationInterpreted against a normal range

DepartmentSpecialist Coagulation
Tube Picture
Collection ConditionsCitrate x 1 (Protein C only). Citrate x 2, EDTA x 1, Serum x 1 (full Thrombophilia screen). Citrate samples full to line please.
Min. Vol 2mL citrated blood

Ref. Range (Male)0.7 - 1.46
Ref. Range (Female)0.7 - 1.46
Ref. Range (Paed)0.7 - 1.46
Ref. Range Notes
IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT7 days
Turnround Comment

Originally edited by : RJAR. Review due on 12/07/2020 16:10:16. Published By Brad Dickinson on 12/07/2019 16:10:16.