|Description||Investigation of platelet function, including platelet aggregation, nucleotide estimation and platelet surface glycoprotein analysis.|
|Indication||Bleeding diatheses where the indication may be due to irregular platelet function.|
|Additional Info||Samples must be delivered to the laboratory by 11:00 am on the day of venepuncture.
This test is only available by specialist request from a Haematology Consultant and should be discussed with a member of the Haemostasis consultant team before arriving into the laboratory. All platelet testing is prearranged with the laboratory before samples are taken to ensure that relevant trained staff are available on the day to process the tests and ensure that we have contact information for the requestor.|
|Concurrent Tests||Platelet glycoproteins/nucleotides.
Full Blood Count and blood film.|
|Dietary Requirements||NO aspirin or aspirin related products for 2 weeks prior to testing|
|Interpretation||Descriptive report of platelet aggregation and glycoproteins is provided. Platelet nucleotides and PFA-100 are reported against a reference range.|
|Collection Conditions||Citrate x 8 minimum (all citrate tubes must be filled to the line). samples must be kept at room temperature and delivered to the laboratory immediately with minimal agitation.|
|Ref. Range (Male)||See note|
|Ref. Range (Female)|| See note|
|Ref. Range (Paed)|| See note|
|Ref. Range Notes||Platelet Aggregation - Qualitative report: interpretive comments added. Platelet nucleotides: Total ATP: 25.5 to 68.9 Total ADP: 12.9 to 39.7 Released ATP: 4.1 to 18.9 Released ADP: 5.3 to 28.5. PFA-100: Collagen/EPI = 85-165secs, Collagen/ADP = 60-120secs. Platelet glycoproteins - interpretive comments added|
|IP Acute TAT||4 weeks|
|IP Routine TAT||4 weeks|
|GP Acute TAT||4 weeks|
|GP Routine TAT||4 weeks|
Originally edited by : RJAR. Review due on 10/01/2020 09:59:05. Published By RJAR on 10/01/2019 09:59:05.