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ID:26 Angiotensin converting enzyme (ACE)
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DescriptionA circulating enzyme marker
IndicationMonitoring treatment of sarcoidosis. Corticosteroids may be titrated against ACE level. Limited value in diagnosis.
Additional InfoConditions in which ACE is raised and may be confused with sarcoidosis include TB, atypical mycobacteria, histoplasmaosis, coccidiodomycosis, allergic alveolitis, berylliosis, Hodgkin's, lung cancer, asbestosis and silicosis. Other causes of a raised ACE include: acute & chronic bronchitis, pulmonary fibrosis, emphysema and bronchial asthma, rheumatoid arthritis, cervical adenitis, connective tissue diseases, Gaucher's, leprosy, untreated hyperthyroidism, fungal disease, alcoholic liver disease, primary biliary cirrhosis and DM.
Concurrent Testsna
Dietary Requirementsna
InterpretationRaised in active sarcoidosis - useful for monitoring. Note a low value of ACE does NOT exclude sarcoid. Enzyme is not specific for sarcoid and is raised in many other conditions some of which may be confused with sarcoid.

DepartmentBiochemistry
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol0.5 mL
Freq.Weekly

Ref. Range (Male)20 - 70
Ref. Range (Female) 20 - 70
Ref. Range (Paed)
Ref. Range Notes
Unitsu/L
IP Acute TATRefer to Website
IP Routine TATRefer to Website
GP Acute TAT- Contact Laboratory
GP Routine TATRefer to Website
Turnround CommentNA

Originally edited by : JHB. Review due on 14/12/2018 16:16:40. Published By Sylvia Mclellan on 14/12/2017 16:16:40.