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ID:237 Vancomycin
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DescriptionVancomycin is a glycopeptide antibiotic used for the treatment of susceptible gram positive infections including MRSA sepsis. The primary aim for monitoring and adjustment of serum Vancomycin concentration is to achieve the serum concentration above the minimum inhibitory concentration and the avoidance of potential adverse effects such as nephrotoxicity or ototoxicity.
Indication
Additional InfoAs of 17.6.11 samples processed in Blood Sciences (Biochemistry) - not Microbiology. Please note: test can only be added to samples within 8 hours of collection
Concurrent Testsna
Dietary Requirementsna
Interpretation Antibiotic. Advice on interpretation can be found via the microbiology section of the Pathology website: http://www.pathology.leedsth.nhs.uk/pathology/Departments/Microbiology/MicroAntibioticMonitoringGuidelines.aspx If you are not able to interpret the vancomycin level result safely please contact the microbiology department for clinical advice.

DepartmentBlood Sciences
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsSerum (with or without gel) and plasma (EDTA/lithium heparin) samples acceptable. Post dose (1hr or 2hrs post dose)
Min. Vol2mL
Freq.7 days a week

Ref. Range (Male)pre: 10 - 15
Ref. Range (Female)pre:10 - 15
Ref. Range (Paed)pre:10 - 15
Ref. Range NotesAdult Ref Range: Pre dose (only) 10-15 mg/L. Pre dose of 15-20 mg/L may be advised in certain infections eg MRSA pneumonia, osteomyelitis, endocarditis & bacteraemia. LTHT do not advocate post dose testing More information at http://www.bris.ac.uk/bcare/AssayBooklet.doc and Leeds Health Pathways (NHS access only))http://www.libraries.leeds.nhs.uk/Resources/Leeds-Health-Pathways.htm
Unitsmg/L
IP Acute TATRefer to Website
IP Routine TATRefer to Website
GP Acute TATSame day
GP Routine TATRefer to Website
Turnround CommentNA

Originally edited by : D Bennett. Review due on 10/06/2015 14:29:48. Published By Sylvia Bennett on 10/06/2014 14:29:48.