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ID:218 Vitamin B1 (Thiamine)
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DescriptionA water soluble vitamin of the B complex. Results are not available on an urgent basis and treatment must not be delayed whilst awaiting a result.
IndicationTest not routinely available without discussion with the Duty Biochemist (x26922).
Additional InfoProtect WHOLE BLOOD sample from light and store in referral samples rack in specimen reception freezer within 2 hours of collection. Do not use any gel tubes. EDTA is the preferred sample type. Lithium heparin tube also acceptable. Sample must reach lab on day of collection preferably within 2 hours
Concurrent Testsna
Dietary RequirementsPatient should be fasted or at least 8h post supplement / TPN
InterpretationVery low levels of thiamine may be associated with beriberi. Severe acute deficiency superimposed on a chronic deficiency may cause cerebral beriberi (Wernicke-Korsakoff syndrome)

DepartmentBiochemistry
SampleBlood
TubeEDTA (Haem)
Tube Picture
Collection ConditionsSample must reach lab on day of collection preferably within 2 hours
Min. Vol50 uL (ideally 100 uL)
Freq.Bi-monthly

Ref. Range (Male)66.5 - 200
Ref. Range (Female)66.5 - 200
Ref. Range (Paed)
Ref. Range NotesMarginal deficiency suggested if <40 nmol/L. Overt deficiency suggested if 5nmol/L or less.
Unitsnmol/L
IP Acute TAT2 weeks
IP Routine TAT2 weeks
GP Acute TAT2 weeks
GP Routine TAT2 weeks
Turnround CommentPaula Marchetti:Paula.marchetti@rothgen.nhs.uk

Originally edited by : KRA. Review due on 21/11/2019 15:02:41. Published By Matthew Clifford on 21/11/2018 15:02:41.