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ID:201 Thyroid Peroxidase Antibodies (TPO)
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DescriptionThyroid peroxidase is the principal antigen against which antibodies are directed in autoimmune thyroid disease.
IndicationDetermining risk of developing hypothyroidism. Confirm that hypothyroidism is due to autoimmune disease.
Additional InfoTPO antibodies are useful in helping to predict those individuals who are at risk of developing hypothyroidism in the future. IF the TSH is raised ie 6-12 IU/L, then positive antibodies predict the development of hypothyroidismn at a rate of approximately 5% per year. TEST CAN ONLY BE ADDED TO SAMPLE WITHIN 72 HOURS OF COLLECTION
Concurrent Testsna
Dietary Requirementsna
InterpretationLevels >200 - women have 5% increase in risk, men have 18-19% increase in risk. Levels >100 confirms autoimmune thyroid disease

DepartmentBiochemistry
SampleBlood
TubeSerum or Heparin
Tube Picture
Collection ConditionsSamples should be sent to Blood Sciences (Biochemistry). **PLEASE NOTE - NOT ANALYSED IN CLINICAL IMMUNOLOGY **. Both serum and lithium heparin samples acceptable
Min. Vol5 mL
Freq.Daily Mon-Fri

Ref. Range (Male)<100
Ref. Range (Female) <100
Ref. Range (Paed)
Ref. Range Notes
Unitsiu/mL
IP Acute TATRefer to Website
IP Routine TATRefer to Website
GP Acute TATRefer to Website
GP Routine TATRefer to Website
Turnround CommentNA

Originally edited by : JHB. Review due on 24/05/2017 07:49:30. Published By Sylvia bennett on 24/05/2016 07:49:30.