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ID:184 Serum Protein Electrophoresis
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DescriptionCapillary zone electrophoresis (CZE) is performed in Immunology. It involves the separation of serum proteins according to their electric charge. This is essential in the investigation of suspected paraproteinaemia / monoclonal gammopathy. Characteristic patterns are also seen in the presence of an acute phase response.
IndicationInvestigation of plasma cell dyscrasia's e.g. Multiple Myeloma.
Additional InfoNew paraproteins identified by electrophoresis are typed by immunofixation and those >3g/L are quantified. It is recommended that urine is also screened by electrophoresis.
Concurrent Testsna
Dietary Requirementsna
InterpretationThe interpretation of a newly identified paraprotein depends on the type of paraprotein, size, rate of change, evidence of end-organ damage and number of plasma cells on bone marrow biopsy.

DepartmentClinical Immunology
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol5ml
Freq.Weekdays

Ref. Range (Male)Descriptive report
Ref. Range (Female)Descriptive report
Ref. Range (Paed)Descriptive report
Ref. Range Notes
Units- Descriptive Report
IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT7 days
Turnround CommentMinimum re-test interval = 180 days

Originally edited by : BD. Review due on 14/09/2018 14:33:50. Published By AM on 14/09/2017 14:33:50.