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ID:155 Phenobarbitone/Primidone
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DescriptionPhenobarbitone is a metabolite of Primidone, use this test to monitor patients on primidone. NOTE: Reporting units changed from mmol/L to mg/L May 1, 2007
IndicationTherapeutic Drug Monitoring.
Additional InfoFor monitoring purposes, blood should not be drawn until a steady state has been attained. This will not be achieved until 2-4 weeks after starting therapy or changing dose. In children the period may be slightly shorter at 1-2 weeks. Renal or hepatic disease may result in increased phenobarbitone concentration. PLEASE NOTE: TEST CAN ONLY BE ADDED TO A SAMPLE WITHIN 8 HOURS OF COLLECTION
Concurrent Testsna
Dietary Requirementsna
InterpretationView results in light of patients clinical status.

DepartmentBlood Sciences
TubeSerum or Heparin
Tube Picture
Collection Conditions Use Gold top (serum gel) tube except for Intensive care units, renal unit, transplant unit, patients on IV heparin (use Green/Yellow top tube for these patients).
Min. Vol1 mL

Ref. Range (Male)10 - 40 mg/L
Ref. Range (Female)10 - 40 mg/L
Ref. Range (Paed)
Ref. Range NotesNOTE: Reporting units changed from mmol/L to mg/L May 1, 2007
IP Acute TAT- Contact Laboratory
IP Routine TAT12 hours
GP Acute TAT- Contact Laboratory
GP Routine TAT24 hours
Turnround CommentNA

Originally edited by : MC. Review due on 24/05/2017 08:00:58. Published By Sylvia McLellan on 24/05/2016 08:00:58.