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ID:154 Pemphigoid/Pemphigus antibodies
Search Links: General Info : Protocols : LabTestsOnline

DescriptionPEMPHIGUS : Autoantibodies directed against desmogleins on the cell surface of epidermal keratinocytes. BULLOUS PEMPHIGOID : Autoantibodies directed against hemidesmosomes in the basement membrane. Both are always tested.
IndicationThese are rare, but serious autoimmune skin diseases. Bullous Pemphigoid - tense blisters, mucosa rarely involved. Pemphigus Vulgaris - flaccid blisters, mucosa often involved.
Additional InfoImmunofluorescence of a skin biopsy should also be performed (by Histopathology) as both assays can give false negative results.
Concurrent Testsna
Dietary Requirementsna
Interpretation70-90% of patients with Pemphigus Vulgaris/ Bullous Pemphigoid have antibodies. Antibody levels may correlate with disease activity for Pemphigus only.

DepartmentClinical Immunology
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsNo restrictions
Min. Vol5 mL
Freq.Weekdays

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesQualitative - neg/pos & titre
Units - Not Defined -
IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT7 days
Turnround CommentNA

Originally edited by : JHB. Review due on 14/09/2018 14:32:42. Published By BD on 14/09/2017 14:32:42.