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ID:153 Parathyroid Hormone (PTH)
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DescriptionThe major hormone involved in Calcium homeostasis.
IndicationInvestigation of disorders of calcium metabolism.
Additional InfoPTH has a marked diurnal rhythm with a nadir at 10-11am. If hyperparathyroidism is suspected, we suggest that samples are taken in the mid morning. Raised levels of PTH are indicative of primary or tertiary hyperparathyroidism. A normal or unmeasurable PTH in a patient with hypocalcaemia is suggestive of hypoparathyroidism. Symptoms of hyperparathyroidism: bones, groans, stones! Bones - increased turnover can cause bone problems. Abdominal groans. Renal stones. Note familial hypocalciuric hypercalcaemia has caused diagnostic problems as the PTH may be raised. Differentiate by measuring calcium in 24 hr urine.
Concurrent TestsCalcium, phosphate and ALP
Dietary Requirementsna
InterpretationResults must be considered in relation to serum Ca. e.g is PTH level appropriate for the Ca. Secondary hyperparathyroidism may be due to renal failure or malabsorption. NB hypocalcaemia may be due to hypomagnasaemia.

DepartmentBlood Sciences
SampleBlood
TubeEDTA (Haem)
Tube Picture
Collection ConditionsSend to laboratory as soon as possible. ***** IMPORTANT Plain/lithium heparin tube also required for Calcium.*****
Min. Vol1 mL
Freq.Weekdays

Ref. Range (Male)1.5 - 7.6 (if normocalcaemic)
Ref. Range (Female)1.5 - 7.6 (if normocalcaemic)
Ref. Range (Paed)
Ref. Range Notes
Unitspmol/L
IP Acute TATSame day
IP Routine TAT48 to 72 hours
GP Acute TAT- Contact Laboratory
GP Routine TAT24 hours
Turnround CommentNA

Originally edited by : MC. Review due on 13/10/2018 15:16:41. Published By SYLVIA BENNETT on 13/10/2017 15:16:41.