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Test and Tubes Database
ID:117 Lithium
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DescriptionDrug used in treatment of depression. Therapeutic concentrations are based on samples taken >12h post dose. Routine monitoring of patients is essential. Patients should also have TFT's monitored.
IndicationTherapeutic Drug Monitoring.
Additional InfoEFFECT OF LITHIUM: <0.4 mmol/L the therapeutic response is poor. Levels between 0.4 - 0.6 mmol/L may possible be beneficial for prophylaxis but the chance of relapse is high. The optimum range is between 0.6 - 0.8 mmol/L. Levels >1.2 mmol/L are associated with the risk of renal impairment. Levels between 1.5 - 3.0 are associated with renal impairment, ataxia, weakness and drowsiness. Above 3.0 mmol/L symptoms include dehydration, confusion, spasticity, seizures and coma.
Concurrent Testsna
Dietary Requirementsna
InterpretationIdeally levels want to be within the target range.

DepartmentBiochemistry
SampleBlood
TubeSerum Gel
Tube Picture
Collection ConditionsMust be > 12 hr post dose.
Min. Vol1 mL
Freq.Weekdays

Ref. Range (Male)0.4 - 1.0
Ref. Range (Female)0.4 - 1.0
Ref. Range (Paed)
Ref. Range Notes
Unitsmmol/L
IP Acute TATRefer to Website
IP Routine TATRefer to Website
GP Acute TAT- Contact Laboratory
GP Routine TATRefer to Website
Turnround CommentNA

Originally edited by : JHB. Review due on 21/06/2017 12:03:46. Published By S.BENNETT on 21/06/2016 12:03:46.