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ID:11 Alanine amino-transferase (ALT)
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DescriptionALT is measured as part of the LFT profile.
IndicationLiver Function Test
Additional InfoALT catalyses the interconversion of amino acids and alpha-ketoacids by transfering amino groups. Present in hepatocyte cytosol. Wide tissue distribution but activity lower than in hepatic tissue. Levels may be raised when there has been damage to skeletal muscle e.g rhabdomyolysis.
Concurrent Testsna
Dietary Requirementsna
InterpretationMarker of hepatocyte damage. Raised in liver disease (e.g. hepatitis, drug damage, fatty liver) and myocardial damage (heart failure leads to back pressure).

DepartmentBiochemistry
SampleBlood
TubeSerum or Heparin
Tube Picture
Collection ConditionsUse Gold top (serum gel) tube except for intensive care units, renal unit, transplant unit, patients on IV heparin (use Green/Yellow top tube for these patients).
Min. Vol1 mL
Freq.Weekdays

Ref. Range (Male)<40
Ref. Range (Female)<40
Ref. Range (Paed)
Ref. Range Notes
Unitsiu/L
IP Acute TATRefer to Website
IP Routine TATRefer to Website
GP Acute TAT- Contact Laboratory
GP Routine TATRefer to Website
Turnround CommentNA

Originally edited by : JHB. Review due on 04/11/2015 11:21:36. Published By Sylvia Bennett on 04/11/2014 11:21:36.