|Description||ALT is measured as part of the LFT profile.|
|Indication||Liver Function Test
|Additional Info||ALT catalyses the interconversion of amino acids and alpha-ketoacids by transfering amino groups. Present in hepatocyte cytosol. Wide tissue distribution but activity lower than in hepatic tissue. Levels may be raised when there has been damage to skeletal muscle e.g rhabdomyolysis.
|Interpretation||Marker of hepatocyte damage. Raised in liver disease (e.g. hepatitis, drug damage, fatty liver) and myocardial damage (heart failure leads to back pressure).
|Tube||Serum or Heparin|
|Collection Conditions||Use Gold top (serum gel) tube except for intensive care units, renal unit, transplant unit, patients on IV heparin (use Green/Yellow top tube for these patients).|
|Min. Vol||1 mL|
|Ref. Range (Male)||<40|
|Ref. Range (Female)||<40|
|Ref. Range (Paed)|| |
|Ref. Range Notes||
|IP Acute TAT||Refer to Website|
|IP Routine TAT||Refer to Website|
|GP Acute TAT||- Contact Laboratory|
|GP Routine TAT||Refer to Website|
Originally edited by : JHB. Review due on 04/11/2015 11:21:36. Published By Sylvia Bennett on 04/11/2014 11:21:36.