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ID:1049 PCR for Tropheryma whipplei
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Description Whipples disease is a rare systemic illness caused by a chronic progressive infection with Tropheryma whipplei. T.whipplei is an intracellular organism, which has most commonly been associated with intermittent arthralgia, chronic digestive problems including diarrhoea and/or weight loss, lymphadenopathy, endocarditis and neurological disease. More recently, it has also been associated with acute infections including gastroenteritis, pneumonia and bacteraemia. PCR is the most common method for detecting this organism because the bacterium cannot be grown using conventional methods.
Indication Clinical suspicion of disease and/or histological observation of bacilli in small bowel specimens.
Additional InfoThis test is only available following discussion with Microbiology. Please discuss with Medical Microbiology (x23962) or x23929. Concurrent Tests: N/A Dietary Requirements: N/A
Concurrent Testsna
Dietary Requirementsna
Interpretation PCR results should be interpreted with other clinical findings. Ideally all positive PCR results should be confirmed with an independent sample

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Collection Conditions Please make sure that the samples are sent in the appropriate specimen container. If unsure, please contact the laboratory.
Min. VolFluid samples should include the cellular component as T.whipplei is an intracellular bacterium. A minimum of 0.5ml is required

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT5 days
IP Routine TAT5 days
GP Acute TAT- Not Defined -
GP Routine TAT- Not Defined -
Turnround CommentNA

Originally edited by : na. Review due on 07/09/2019 09:47:28. Published By on 07/09/2018 09:47:28.