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ID:1026 MTB complex identification by PCR
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Description Tuberculosis is caused by members of the Mycobacterium tuberculosis complex group of bacteria including M.tuberculosis, M.africanum, M.bovis, M.bovis BCG and M.microti (these are the most common species encountered, but is not exhaustive). These closely related species differ in host range and pathogenicity but cannot be differentiated by simple PCR for detection of M.tuberculosis complex. Samples are tested using the PCR -line probe assay GenoType MTBC assay (Hain LifeScience).
Indication This assay is available following discussion with a Microbiology Consultant or Specialist Clinical Scientist. It is useful where M.bovis infection is suspected because M.bovis is intrinsically resistant to pyrazinamide. It can also be used to confirm whether infection is associated with BCG vaccination or immunotherapy.
Additional Info Specimens will require a positive M.tuberculosis complex PCR before testing to ensure sufficient DNA available for successful testing.
Concurrent TestsMycobacterium TB PCR
Dietary Requirementsna
Interpretation This PCR assay uses the Hain GenoType MTBC kit to differentiate members of the M.tuberculosis complex.

DepartmentMicrobiology
SampleVarious
Tube
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Collection Conditions Please make sure that the samples are sent in the appropriate specimen container. If unsure please contact the laboratory.
Min. Vol
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Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT14 days
IP Routine TAT14 days
GP Acute TAT14 days
GP Routine TAT14 days
Turnround CommentNA

Originally edited by : na. Review due on 17/07/2018 10:10:52. Published By on 17/07/2017 10:10:52.