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ID:1017 Gastric Intrinsic Factor Antibodies (GIFab)
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Description The autoimmune destruction of gastric parietal cells (and autoantibody inactivation of intrinsic factor) leads to a lack of intrinsic factor. Since the absorption from the gut of normal dietary amounts of vitamin B12 is dependent on intrinsic factor, the loss of intrinsic factor leads to vitamin B12 deficiency. The loss of ability to absorb vitamin B12 is the most common cause of adult vitamin B12 deficiency.
Indication As a follow up test to a reduced vitamin B12 result.
Additional Info A GIFab sample should not be collected from a patient who has received a vitamin B12 injection in the last week as free vitamin B12 can give a false positive result.
Concurrent TestsVitamin B12
Dietary Requirementsna
Interpretation Reported as present, not detected or equivocal.

DepartmentBlood Sciences
TubeSerum Gel
Tube Picture
Collection ConditionsSamples must be less than 48 hours old when received in the laboratory. Samples from external referral sites must be separated and frozen prior to transport.
Min. Vol 2ml

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -
IP Acute TAT- Not Defined -
IP Routine TAT15 days
GP Acute TAT- Not Defined -
GP Routine TAT15 days
Turnround CommentNA

Originally edited by : RJAR. Review due on 20/02/2019 14:47:22. Published By MPC on 20/02/2018 14:47:22.