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Description JC virus [JCV] is ubiquitous causing subclinical infection within the first 10-15 years of life. The virus usually remains latent in healthy individuals, only causing disease when the immune system is severely compromised. JCV is a causative agent of progressive multifocal leukoencephalopathy (PML), which has been studied in patients with HIV infection, cancer and those who have received kidney or bone-marrow transplants. There is also an association between PML and use of some monoclonal antibodies.
Indication Consider in immunocompromised patients with progressive damage and inflammation of the white matter in the brain with neurological symptoms including: cognitive and behavioural changes; paraesthesia; visual problems; gait abnormalities and loss of limb coordination; and hemiparesis.
Additional Info- Please specify if patient is immunocompromised and has PML
Concurrent Tests
Dietary Requirementsna


Ref. Range (Male)N/A
Ref. Range (Female)N/A
Ref. Range (Paed)N/A
Ref. Range Notes
Units- Descriptive Report

Other Help:National Laboratory Medicine Handbook

IP Acute TAT8 days
IP Routine TAT8 days
GP Acute TAT8 days
GP Routine TAT8 days
Turnround CommentNA
Originally edited by : B .Saundh. Last edited on 05/05/2018 11:41:05. Published By K Roberts on 05/05/2017 11:41:05.