Trust Homepage > Pathology Homepage

Test and Tubes Database
ID:935 Procalcitonin
Search Links: General Info : Protocols : Patient Info

DescriptionProcalcitonin is a precursor to the hormone calcitonin, a relatively specific marker for severe bacterial infection in patients with suspected sepsis. ****PLEASE NOTE - This test is only offered to a specific cohort of patients as part of a study. Requests from other areas will NOT be processed ****
Indication
Additional InfoProcalcitonin is normally produced by the parafollicular cells of the thyroid but can also be produced by the neuroendocrine cellls of the lung and the intestine in response to proinflammatory stimuli. Elevated procalcitonin concentrations occur in systemic bacterial infections. Relatively low concentrations are seen with viral infections or inflammatory diseases. Procalcitonin is more sensitive than CRP in discriminating between bacterial and viral infections. Low procalcitonin predicts the absence of bacteraemia/sepsis. An increase in procalcitonin, in response to infection occurs before a rise in CRP.
Concurrent Testsna
Dietary Requirementsna

Interpretation Elevated procalcitonin concentrations occur in systemic bacterial infections. Relatively lowconcentrations are seen with viral infections or inflammatory diseases. Procalcitonin is more sensitivethan CRP in discriminating between bacterial and viral infections. Low procalcitonin predicts the absence of bacteraemia/sepsis. An increase in procalcitonin, in response to infection occurs before a rise in CRP.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -


IP Acute TAT- Not Defined -
IP Routine TAT- Not Defined -
GP Acute TAT- Not Defined -
GP Routine TAT- Not Defined -
Turnround CommentNA
Originally edited by : Adrian Miller. Last edited on 01/06/2018 11:54:58. Published By Matthew Clifford on 01/06/2017 11:54:58.