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ID:912 Orexin (CSF)
Search Links: General Info : Protocols : Patient Info

DescriptionInvestigation of narcolepsy and other neurological sleep disturbances. Orexin (also see Hypocretin) is a neurotransmitter that regulates wakefulness and appetite. The most common form of narcolepsy, in which the sufferer briefly loses muscle tone (cataplexy), is caused by a lack of Orexin in the brain.
Additional InfoN.B. No serum sample required
Concurrent Testsna
Dietary Requirementsna


Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes Normal: >200 pg/mL; Intermediate: 100-200 pg/mL; Low: <100 pg/mL; Highly suggestive of narcolepsy/cataplexy: <50 pg/mL. Intermediate and low values are occassionally found in patients with other neurological diseases associated with sleep disturbance

Other Help:National Laboratory Medicine Handbook

IP Acute TATAt least 4 weeks
IP Routine TATAt least 4 weeks
GP Acute TATAt least 4 weeks
GP Routine TATAt least 4 weeks
Turnround CommentSarosh
Originally edited by : dan carless. Last edited on 17/10/2017. Published By dan carless on 17/10/2017.