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Test and Tubes Database
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DescriptionT-Spot TB is a blood test to detect previous exposure to Mycobacterium tuberculosis (TB). This is by the detection of Interferon Gamma production by T- Cells which recognise specific antigens. It is not affected by prior HBG vaccination. The test is primarily for the detection of latent tuberculosis as opposed to active clinical disease. For the latter, suitable fresh (ie NOT in formalin) samples for AFB microscopy and culture are the microbiological diagnostic specimen of choice.
Indication Diagnosis of Tuberculosis infection in notably immunocomprimised patients or in whom an indeterminate Quanteferon result has been obtained. Aid to diagnosis of active disease in partients where suitable samples for AFB cannot be obtained (requires Microbiologist approval)
Additional Info Tubes must reach the Microbiology Laboratory, Old Medical School, LGI by 16:00 hrs on the day of sample collection which can be Monday - Friday. (For BRI specimens, this means 14:30 at the BRI Laboratory) In Immuno-compromised patients, larger blood volumes may required.
Concurrent Testsna
Dietary Requirementsna


Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range Notes
Units - Not Defined -

IP Acute TAT14 days
IP Routine TAT14 days
GP Acute TAT14 days
GP Routine TAT14 days
Turnround CommentNA
Originally edited by : Dr T Collyns. Last edited on 04/07/2017 10:08:11. Published By K Roberts on 04/07/2016 10:08:11.