|Description||Syphilis is an infectious disease caused by the spirochete Treponema pallidum. It almost always is transmitted by sexual contact with infectious lesions, but it also can be transmitted in utero and via blood transfusion. Can cause memory loss and dementia.
Pathophysiology: T pallidum is a fragile spiral bacterium 6-15 micrometers long by 0.25 micrometers in diameterT pallidum penetrates abraded skin or intact mucous membranes easily and disseminates rapidly, although asymptomatically, via the blood vessels and lymphatics
Laboratory: Positive screening tests confirmed by IgM(acute), RPR(acute and falls with successful treatment) and TPPA (long standing)|