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ID:721 Procollagen 1 (P1NP)
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DescriptionAlso known as procollagen extension peptide. Procollagen 1 (P1NP) concentrations reflect osteoblast activity so any disease increasing the activity of osteoblasts or activation frequency of the bone forming unit will result in elevated P1NP concentrations. Low P1NP may indicate adynamic bone. This test is currently only available for Dr SM Orme for monitoring Teriperatide therapy.
Indication P1NP is useful in monitoring response to anti-resorption therapy.
Additional InfoP1NP shows minimal circadian rhythm or seasonal variation and food intake or diet show no detectable influence on serum levels.
Concurrent Testsna
Dietary Requirementsna

InterpretationA baseline pre-treatment measurement is required if assessing response to antiresorption therapy.

Ref. Range (Male)20-76 ug/L
Ref. Range (Female)premenopausal 30-78 ug/L
Ref. Range (Paed)
Ref. Range Notespostmenopausal females 26-110 ug/L
Units - Not Defined -


IP Acute TAT2 weeks
IP Routine TAT2 weeks
GP Acute TAT2 weeks
GP Routine TAT2 weeks
Turnround CommentDr Allison Chipchase:allison.chipchase@nnuh.nhs.uk
Originally edited by : J H Barth. Last edited on 17/10/2017. Published By dan carless on 17/10/2017.