|ID:706 ||BK virus||Search Links: General Info : Protocols : Patient Info|
|Description||The BK virus was first isolated in 1971 from the urine of a renal transplant patient, initials B.K. The BK virus is similar to another virus called the JCVirus since their genome sequences share 75% homology. Both of these viruses can be identified and differentiated from each other by carrying out serological tests using specific antibodies or by using a PCR based genotyping approach|
|Additional Info||The BK virus rarely causes disease since many people who are infected with this virus are asymptomatic. If symptoms do appear, they tend to be mild: respiratory infection or fever. These are known as primary BK infections.
The virus then disseminates to the kidneys and urinary tract where it persists for the life of the individual. It is thought that up to 80% of the population contains a latent form of this virus, which remains latent until the body undergoes some form of immunosuppression. Typically, this is in the setting of kidney transplantation or multi-organ transplantation. Presentation in these immunocompromised individuals is much more severe. Clinical manifestations include renal dysfunction (seen by a progressive rise in serum creatinine), and an abnormal urinalysis revealing renal tubular cells and inflammatory cells.|
|Ref. Range (Male)|| |
|Ref. Range (Female)|| |
|Ref. Range (Paed)|| |
|Ref. Range Notes|| |
|Units|| - Not Defined -|
|IP Acute TAT||8 days|
|IP Routine TAT||8 days|
|GP Acute TAT||8 days|
|GP Routine TAT||8 days|
|Turnround Comment||Results may be available considerably earlier than stated turnaround time.|
Originally edited by : D Bennett. Last edited on 27/06/2017 16:40:39. Published By K Roberts on 27/06/2016 16:40:39.