|ID:583 ||Alcohol and acid fast bacilli (AAFB) culture - General Information||Search Links: General Info : Protocols : Patient Info|
|Description||85% of clinical tuberculosis cases present as pulmonary tuberculosis. Extrapulmonary tuberculosis can affect all organs with miliary tuberculosis and tuberculous meningitis being very serious disease presentations. Tuberculous lymphadenitis, abdominal tuberculosis, "cold" abscesses and skeletal tuberculosis are other sites. Latent tuberculosis denotes a condition when patients are infected with tuberculosis but show no clinical symptoms. Latently infected patients are not infectious to others but carry a 10% lifetime risk of developing active i.e. clinical TB with the highest risk of developing active disease within 2 years after becoming latently infected. Tuberculin skin testing (Mantoux testing) is the current diagnostic standard but gamma-interferon testing (Quantiferon-Gold)offers an alternative for selected patients.|
|Additional Info||Auramine staining of tissue samples is carried out within 24-48 hrs after receipt of samples but microscopy is less sensitive than culture. In selected patients TB PCR can be of value but this has to be discussed with a microbiologist prior to testing.|
|Interpretation||Preliminary microscopy results will be reported negative or positive with a quantitative indication.
Initial culture results will be reported as AAFB isolated with confirmation of final identification and sensitivities reported later|
|Ref. Range (Male)|| |
|Ref. Range (Female)|| |
|Ref. Range (Paed)|| |
|Ref. Range Notes||
|Units|| - Not Defined -|
|IP Acute TAT||60 days|
|IP Routine TAT||60 days|
|GP Acute TAT||60 days|
|GP Routine TAT||60 days|
|Turnround Comment||Microscopy for AAFB will be available within 24 hours for samples received Monday to Friday before 12pm. Microscopy TAT for samples received at weekends and bank holidays will be 3 days.
Culture 60 days
Turnaround time may be increased if prolonged incubation is clinically indicated.|
Originally edited by : Dr. H. Schuster. Last edited on 30/11/2018 12:24:26. Published By K Roberts on 30/11/2017 12:24:26.