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ID:537 Histoplasma antibodies
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DescriptionThis test detects the presence of antibodies to Histoplasma capsulatum. This test comprises two separate tests: A manual double diffusion (DD) for precipitins and a complement fixation testing (CFT) using commercial reagents.
IndicationThis test is appropriate for the diagnosis of histoplasmosis.
Additional InfoThis test comprises of two separate tests: A double diffusion test for precipitins (DD) and a complement fixation test (CFT).
Concurrent Testsna
Dietary Requirementsna

InterpretationA positive CFT titre of 1/8 or greater and a positive M or H band by DD is a clear indication of histoplasmosis. Positive CFT titres less than 1/8 or CFT results in the absence of a positive DD result are likely to be false positives and may relate to high levels of antibody to Aspergillus which is worth testing for.

Ref. Range (Male)DD negative CFT < 1/8
Ref. Range (Female)DD negative CFT < 1/8
Ref. Range (Paed)DD negative CFT < 1/8
Ref. Range NotesThis test involves 2 assays, a complement fixation test (CFT) and an double diffusion (DD) test. The CFT test is reported against both yeast and mycelial antigens. The DD test reports against M and/or H bands positivity.
Units - Not Defined -


IP Acute TAT14 days
IP Routine TAT14 days
GP Acute TAT14 days
GP Routine TAT14 days
Turnround Comment95% turnaround times The DD test is performed daily. The CFT is performed once a week. Results may be available considerably earlier than stated turnaround time.
Originally edited by : Richard Barton. Last edited on 14/07/2018 13:02:30. Published By on 14/07/2017 13:02:30.