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Test and Tubes Database
ID:411 Pro-insulin
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DescriptionPro-insulin is secreted in excess by insulinomas due to a shortened storage phase. Pro-insulin has 10% of the hypoglycaemic effect of insulin, but it accounts for 25% of immunoreactive insulin.
IndicationSuspicion of an insulinoma
Additional Info
Concurrent Testsna
Dietary Requirementsna

InterpretationExcess levels reliably indicate an insulinoma. High proportion of pro-insulin to insulin indicates an undifferentiated tumour e.g. an islet cell carcinoma.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesFor hypoglycaemic samples: <10 pmol/L
Units - Not Defined -


IP Acute TAT2 weeks
IP Routine TAT2 weeks
GP Acute TAT2 weeks
GP Routine TAT2 weeks
Turnround CommentDr G Wark:gwen.wark@nhs.net
Originally edited by : . Last edited on 17/10/2017. Published By on 17/10/2017.