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ID:393 Amitriptyline/Nortriptyline
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DescriptionNortriptyline is the N-methylated metabolite of amitriptyline. Both are tricyclic antidepressants with mild tranquilising action. They inhibit catecholamine reuptake.
IndicationInvestigation into toxicity.
Additional Info
Concurrent Testsna
Dietary Requirementsna

InterpretationAmitriptyline half-life 10 -28 hrs. Nortriptyline half-life 18-60 hrs.

Ref. Range (Male)See note
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesTherapeutic range: 30-150 ug/L
Unitsug/L


IP Acute TATAt least 1 week
IP Routine TATAt least 1 week
GP Acute TATAt least 1 week
GP Routine TATAt least 1 week
Turnround CommentNA
Originally edited by : . Last edited on 31/10/2018 15:03:50. Published By on 31/10/2017 15:03:50.