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ID:154 Pemphigoid/Pemphigus antibodies
Search Links: General Info : Protocols : Patient Info

DescriptionPEMPHIGUS : Autoantibodies directed against desmogleins on the cell surface of epidermal keratinocytes. BULLOUS PEMPHIGOID : Autoantibodies directed against hemidesmosomes in the basement membrane. Both are always tested.
IndicationThese are rare, but serious autoimmune skin diseases. Bullous Pemphigoid - tense blisters, mucosa rarely involved. Pemphigus Vulgaris - flaccid blisters, mucosa often involved.
Additional InfoImmunofluorescence of a skin biopsy should also be performed (by Histopathology) as both assays can give false negative results.
Concurrent Testsna
Dietary Requirementsna

Interpretation70-90% of patients with Pemphigus Vulgaris/ Bullous Pemphigoid have antibodies. Antibody levels may correlate with disease activity for Pemphigus only.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesQualitative - neg/pos & titre
Units - Not Defined -

IP Acute TAT- Contact Laboratory
IP Routine TAT7 days
GP Acute TAT- Contact Laboratory
GP Routine TAT7 days
Turnround CommentNA
Originally edited by : JHB. Last edited on 14/09/2018 14:32:42. Published By BD on 14/09/2017 14:32:42.