Trust Homepage > Pathology Homepage

Test and Tubes Database
ID:1050 PFA-100
Search Links: General Info : Protocols : Patient Info

Description**PLEASE NOTE - FROM JUNE 2019 THIS ASSAY WILL NO LONGER BE AVAILABLE** The PFA 100 is an instrument and test cartridge system in which the process of platelet adhesion and aggregation following vascular injury is simulated in vitro. Platelet dysfunction detected by the PFA-100 system may be acquired, inherited, or induced by platelet inhibiting agents. The most common causes of platelet dysfunction are related to uraemia, von Willebrand disease (VWD), and exposure to agents, such as acetyl salicylic acid (ASA, for example Aspirin).
IndicationBleeding diatheses where the indication may be due to irregular platelet function.
Additional InfoUsually requested as part of a full platelet function study. See also Platelet Function Tests.
Concurrent TestsPlatelet Aggregation Studies, Platelet Glycoproteins, Platelet Nucleotides, Full Blood Count, Blood film.
Dietary Requirementsna

InterpretationIncreased closure times to both Coll/Epi and Coll/ADP cartridge would indicate a platelet function defect (results affected by low haematocrit and platelet count). Increased closure time to Coll/Epi cartridge only would indicate a drug induced platelet function defect.

Ref. Range (Male)
Ref. Range (Female)
Ref. Range (Paed)
Ref. Range NotesMale - Col/EPI = 85 165 secs Col/ADP = 60 120 secs. Female - Col/EPI = 85 165 secs Col/ADP = 60 120 secs

Other Help:National Laboratory Medicine Handbook

IP Acute TAT4 weeks
IP Routine TAT4 weeks
GP Acute TAT4 weeks
GP Routine TAT4 weeks
Turnround CommentNA
Originally edited by : na. Last edited on 13/06/2020 14:53:30. Published By on 13/06/2019 14:53:30.