Specialist Laboratory Medicine

The Department of Specialist Laboratory Medicine was formed in April 2009 and incorporates specialist biochemistry, immunology and haematology services not provided within the automated Blood Sciences laboratories.

For a list of tests performed by SLM and their accreditation status please click the following link: SLM tests accreditation status


Clinical Immunology - autoantibody, immunochemistry, allergy and Immune deficiency

Investigations, Cellular/Transplant service, Immunosuppressant monitoring.

Transplant Immunology (Histocompatibility and Immunogenetics) -Tissue Typing, lab support in renal and bone marrow transplant programs, HLA disease association markers.

Cellular Immunology - Regional CD4 monitoring service, lab support in primary and secondary immunodeficiencies.

Biochemical Genetics:

Screening Laboratory: regional neonatal screening service and antenatal screening for Down's syndrome.

Metabolic Laboratory: investigations for inborn errors of metabolism.


SAS hormones service, manual and automated immunoassays for adrenal and gonadal steroid hormones and peptide hormones, mass spectrometry assay service for steroid hormones and 25(0H) vitamin D

Toxicology, Trace Metals and Metabolics:

Drugs of abuse screening, nutritional and toxicological measurements of trace metals

SAS trace metal service, Drugs of abuse measurement in urine and oral fluid

metabolic laboratory studies,Vitamin A and E, biochemical markers for carcinoid syndrome, biochemical markers for phaeochromocytoma


Full clinical and laboratory service for the investigation of management of patients with the porphyrias.

Specialist Haematology:

Haemostasis and Thrombosis, morphology and specialist assays, Haemoglobinopathy screening and Leeds Anticoagulant Service.

SLM Departmental Location

The Specialist Laboratory Medicine department manages laboratories on four hospital sites in support of the activity of the Leeds Teaching Hospitals NHS Trusts, Primary Care Trusts and Community Mental Health Trusts. It provides services in support of approximately 3500 beds including a large contingent of specialist ITU and HDU beds in paediatrics, neonatal care, general medicine and surgery, transplantation, neurosurgery and cardiothoracic surgery. Many of the laboratory specialties draw referrals from across the Yorkshire region and beyond.

  • Wharfedale (Anticoagulant management only)
  • St. James University Hospital site (SJUh)
  • Leeds General Infirmary site (LGI)

Departmental Service Principles

The Department will endeavor to provide services which are based on the following principles:

  • Services will be patient focused
  • Services will be appropriate to clinical demand
  • Services will be based on knowledge-based practices
  • Provision will be flexible to changing service needs
  • The Department will be responsible in its use of resources
  • The Department is committed to widening its horizons and those of its staff and its users

Page updated: 06/08/2019 | Updated by: Michael O'Sullivan