Specialist Laboratory Medicine

Specialist Laboratory Medicine encompasses specialist testing within the specialties of Biochemistry, Haematology and Immunology. We are a referral lab for non-specialist laboratories within the WYAAT region and beyond. We support specialist clinical services that are commissioned by NHS England, such as the Newborn screening programme, Haemoglobinopathy screening and the Regional Haemophilia Network. See below for details of our sub-disciplines.

For a list of tests performed by SLM and their accreditation status please click the following link: SLM tests accreditation status


Clinical Immunology

Autoantibody measurement


Allergy and Immune deficiency

Transplant Immunology (Histocompatibility and Immunogenetics)

Tissue Typing

lab support in renal and bone marrow transplant programs

HLA disease association markers

Cellular Immunology

Regional CD4 monitoring service

Diagnosis and monitoring of primary and secondary immunodeficiencies.

Biochemical Genetics

Diagnosis and monitoring of patients with inherited metabolic disorders.


SAS hormones service, manual and automated immunoassays for adrenal and gonadal steroid hormones and peptide hormones, mass spectrometry assay service for steroid hormones and 25(0H) vitamin D

Toxicology, Trace Metals and Metabolics:

Drugs of abuse testing in urine

SAS Trace Elements laboratory - Nutritional and Toxicological measurements of trace metals

Vitamin A and E analysis

Biochemical markers for carcinoid syndrome

Biochemical markers for pheochromocytoma

Measurement of urine porphobilinogen (PBG) for acute porphyria

Specialist Haematology:

Haemostasis and Thrombosis

Specialist Coagulation

Haemoglobinopathy screening

SLM Departmental Location

The Specialist Laboratory Medicine department manages laboratories on four hospital sites in support of the activity of the Leeds Teaching Hospitals NHS Trusts, Primary Care Trusts and Community Mental Health Trusts. It provides services in support of approximately 3500 beds including a large contingent of specialist ITU and HDU beds in paediatrics, neonatal care, general medicine and surgery, transplantation, neurosurgery and cardiothoracic surgery. Many of the laboratory specialties draw referrals from across the Yorkshire region and beyond.

  • Wharfedale (Anticoagulant management only)
  • St. James University Hospital site (SJUh)
  • Leeds General Infirmary site (LGI)

Departmental Service Principles

The Department will endeavor to provide services which are based on the following principles:

  • Services will be patient focused
  • Services will be appropriate to clinical demand
  • Services will be based on knowledge-based practices
  • Provision will be flexible to changing service needs
  • The Department will be responsible in its use of resources
  • The Department is committed to widening its horizons and those of its staff and its users

Page updated: 06/08/2019 | Updated by: Michael O'Sullivan